Recent publications

See also the links to GoogleScholar for full publication lists of each PI


Zhernakova DV, de Klerk E, Westra H-J, Mastrokolias A, Amini S, et al. (2013) DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts. PLoS Genet 9(6): e1003594. Full text

Kumar V, Westra HJ, Karjalainen J, Zhernakova DV, … Franke L, Wijmenga C. Human disease-associated genetic variation impacts large intergenic non-coding RNA expression. PLoS Genet 2013;9(1):e1003201. Full text

Boomsma, D. I., Wijmenga, C., Slagboom, E. P., Swertz, M. A., Karssen, L. C., Abdellaoui, A., et al. (2013). The Genome of the Netherlands: design, and project goals. Eur J Hum Gen.  Full text (position paper)

Snoek LB, Van der Velde KJ, Arends D, Li Y, Beyer A, Elvin M, Fisher J, Hajnal A, Hengartner MO, Poulin GB, Rodriguez M, Schmid T, Schrimpf S, Xue F, Jansen RC, Kammenga JE, Swertz MA. WormQTL–public archive and analysis web portal for  natural variation data in Caenorhabditis spp. Nucleic Acids Res. 2013 Jan;41 (Database issue):D738-43. Full text

Rietveld CA, et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. 2013 Jun 21;340(6139):1467-1471. Abstract

Romanos J, Rosén A, Kumar V, Trynka G, Franke L, … Wijmenga C; PreventCD Group. Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. Gut. 2013 Jun 7.  Full text

Trouw LA, et al. Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis. Clin Exp Immunol. 2013 Jul;173(1):76-83. Abstract

Ganesh SK, et al. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. 2013;22(8):1663-78. Abstract


Fu J, Wolfs MG, … Hofker MH, Wijmenga C, Franke L. Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet. 2012 Jan;8(1):e1002431. Full text

Durrant C, Swertz MA, Alberts R, Arends D, Möller S, Mott R, Prins P, van der Velde KJ, Jansen RC, Schughart K. Bioinformatics tools and database resources for systems genetics analysis in mice–a short review and an evaluation of future needs. Brief Bioinform. 2012 Mar;13(2):135-42. Full text

Arends D, van der Velde KJ, Prins P, Broman KW, Möller S, Jansen RC, Swertz MA. xQTL workbench: a scalable web environment for multi-level QTL analysis. Bioinformatics. 2012 Apr 1;28(7):1042-4. Full text

Asselbergs FW et al. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet. 2012;91(5):823-38. Full text

Dolmans GH, Werker PM, de Jong IJ, Nijman RJ; LifeLines Cohort Study, Wijmenga C, Ophoff RA. WNT2 locus is involved in genetic susceptibility of Peyronie’s disease. J Sex Med. 2012;9(5):1430-4. Abstract


Dolmans GH, … LifeLines Cohort Study; BSSH-GODD Consortium. Wnt signaling and Dupuytren’s disease. N Engl J Med. 2011;365(4):307-17. Full text


Earlier relevant papers

Brandsma M, van Ommen GJ, Wijmenga C, Kiemeney LA. [Dutch government invests in existing biobanks]. Ned Tijdschr Geneeskd. 2010;154:A2825; in Dutch. Abstract

Franke L, de Kovel CG, Aulchenko YS, Trynka G, Zhernakova A, Hunt KA, Blauw HM, van den Berg LH, Ophoff R, Deloukas P, van Heel DA, Wijmenga C. Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays. Am J Hum Genet. 2008 Jun;82(6):1316-33. Full text